中文名 | 银杏内酯 J |
英文名 | Ginkgolide J |
别名 | 银杏内酯J 银杏内酯 J 白果苦内酯 J 银杏内酯J(标准品) 银杏内酯J(白果苦内酯J) 银杏内酯 J, 来源于银杏叶 GINKGOLIDE J 银杏内酯J |
英文别名 | BN 52024 J Ginkgoli Ginkgolide J GINKGOLIDE J 7beta-hydroxyginkgolide a GinkgolideA, 7-hydroxy-, (7β)- |
CAS | 107438-79-9 |
化学式 | C20H24O10 |
分子量 | 424.4 |
InChI | InChI=1/C20H24O10/c1-6-12(23)27-7-5-17-11-8(21)9(16(2,3)4)18(17)10(22)13(24)29-15(18)30-20(17,14(25)28-11)19(6,7)26/h6-11,15,21-22,26H,5H2,1-4H3/t6-,7+,8-,9+,10?,11-,15+,17?,18?,19-,20+/m1/s1 |
密度 | 1?+-.0.1 g/cm3(Predicted) |
熔点 | >282oC (dec.) |
沸点 | 760.4±60.0 °C(Predicted) |
比旋光度 | -11.8° (c=1,Ethanol) |
闪点 | 273.6°C |
蒸汽压 | 1.09E-26mmHg at 25°C |
溶解度 | DMSO (微溶) 、乙醇 (微溶) 、甲醇 (微溶) |
折射率 | 1.65 |
酸度系数 | 11.28±0.70(Predicted) |
存储条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
外观 | 整洁 |
颜色 | White |
物化性质 | 白色结晶粉末,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于银杏叶。 |
MDL号 | MFCD03093737 |
体内研究 | Ginkgolide J (100 μM) treatment reduces the apoptotic damage induced by serum deprivation (24h) or treatment with Staurosporine (200 nM, 24h) in cultured chick embryonic neurons. |
WGK Germany | 3 |
参考资料 展开查看 | 1. [IF=3.935] Xingliang Niu et al."Hydrogen/deuterium exchange, a unique and effective method for MS fragmentation behavior elucidation of ginkgolides and its application to systematic research in Ginkgo biloba."J Pharmaceut Biomed. 2017 Feb;134:181 2. [IF=4.098] Yi Zhong et al."An online, non-destructive method for simultaneously detecting chemical, biological, and physical properties of herbal injections using hyperspectral imaging with artificial intelligence."Spectrochim Acta A. 2022 Jan;264:120250 3. [IF=3.935] Yi Zhong et al."A strategy for identifying effective and risk compounds of botanical drugs with LC-QTOF-MS and network analysis: A case study of Ginkgo biloba preparation."J Pharmaceut Biomed. 2021 Jan;193:113759 4. [IF=3.935] Yongyi Li et al."Integrated molecular networking strategy enhance the accuracy and visualization of components identification: A case study of Ginkgo biloba leaf extract."J Pharmaceut Biomed. 2022 Feb;209:114523 |
微信搜索化工百科或扫描下方二维码,添加化工百科小程序,随时随地查信息!